Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173522 | 0.86 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL11452323 | 0.78 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL31525212 | 0.78 | PPARA (0.54) | PPARGPPARA | |
| SCHEMBL11383703 | 0.78 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL11883894 | 0.77 | PPARG (0.47) | PPARGPPARA | |
| Hydrochloric Acid SCHEMBL30873686 | 0.77 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL4689279 | 0.74 | POLB (0.62) | PPARGPPARA | |
| SCHEMBL1874697 | 0.73 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL5730399 | 0.72 | MAOB (0.42) | PPARGPPARA | |
| SCHEMBL3028298 | 0.71 | PPARA (0.68) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923372-A4 | PYRIDINONE THROMBIN INHIBITORS | MERCK & CO INC (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0923372-A1 | PYRIDINONE THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5792779-A | CARDIOVASCULAR DISORDERS; ANGINA | MERCK & CO., INC. (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1997030708-A1 | PYRIDINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1997-08-28 | — | — | WO | disclosed |