Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370915 | 0.86 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL4187184 | 0.84 | LDHA (0.61) | PPARGPPARA | |
| SCHEMBL1874697 | 0.84 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL4170587 | 0.83 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL4180715 | 0.82 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL4183099 | 0.82 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL8935879 | 0.82 | PPARA (0.68) | PPARGPPARA | |
| SCHEMBL21057159 | 0.82 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL21057157 | 0.82 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL3028298 | 0.82 | PPARA (0.68) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227680-A1 | Amino Acid Derivatives | PFIZER, INC. (US) | 2009-09-10 | — | — | US | claimed |
| EP-1951655-A2 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-08-06 | — | — | EP | claimed |
| WO-2007057767-A2 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | claimed |
| US-20090227680-A1 | Amino Acid Derivatives | PFIZER, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| EP-1951655-A2 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057767-A2 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227680-A1 | Amino Acid Derivatives | OPRL1, OPRK1, AVPR1A | PPARG 2322/4885PPARA 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.