Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 3/20 | 0.30 |
| ▸ | ARG2 | P78540 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442710 | 1.00 | NOS2 (0.48) | NOS2ANPEPARG1ARG2 | |
| Hydrochloric Acid SCHEMBL7373039 | 0.98 | NOS2 (0.47) | NOS2ANPEPARG2 | |
| Hydrochloric Acid SCHEMBL8832387 | 0.98 | NOS2 (0.47) | NOS2ANPEPARG2 | |
| SCHEMBL7374183 | 0.92 | — | — | |
| SCHEMBL7373861 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL7721003 | 0.90 | NOS2 (0.48) | NOS2ANPEP | |
| Hydrochloric Acid SCHEMBL7371540 | 0.90 | NOS2 (0.48) | NOS2ANPEP | |
| SCHEMBL21067370 | 0.77 | NOS2 (0.50) | NOS2ANPEP | |
| SCHEMBL21067372 | 0.77 | NOS2 (0.50) | NOS2ANPEP | |
| SCHEMBL7131728 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| US-6060462-A | Electrophilic peptide analogs as inhibitors of trypsin-like enzymes | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |
| EP-0724446-A4 | ELECTROPHILIC PEPTIDE ANALOGS AS INHIBITORS OF TRYPSIN-LIKE ENZYMES | DU PONT MERCK PHARMA (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |
| EP-0724446-A1 | ELECTROPHILIC PEPTIDE ANALOGS AS INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995009634-A1 | ELECTROPHILIC PEPTIDE ANALOGS AS INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-13 | — | — | WO | disclosed |