Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.48 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372097 | 0.98 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7751053 | 0.97 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7372942 | 0.97 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7377178 | 0.92 | RECQL (0.45) | AVPR2MEN1GAAKMT2ACYP1A2 | |
| SCHEMBL7376322 | 0.92 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7371692 | 0.91 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7749486 | 0.91 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7371254 | 0.91 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BGAA | |
| SCHEMBL7371629 | 0.90 | NPSR1 (0.42) | AVPR2AVPR1AAVPR1BMEN1GAA | |
| SCHEMBL7375946 | 0.90 | NPSR1 (0.42) | AVPR2AVPR1AAVPR1BMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |