Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371914 | 0.94 | POLB (0.45) | RECQLMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7370995 | 0.92 | AVPR2 (0.48) | MEN1KMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7372097 | 0.91 | AVPR2 (0.46) | AVPR2GAA | |
| SCHEMBL7372942 | 0.91 | AVPR2 (0.46) | AVPR2GAA | |
| SCHEMBL7751053 | 0.91 | AVPR2 (0.46) | AVPR2GAA | |
| SCHEMBL7371254 | 0.91 | AVPR2 (0.41) | RECQLAVPR2GAA | |
| SCHEMBL7373823 | 0.90 | AVPR2 (0.39) | RECQLMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7373825 | 0.90 | AVPR2 (0.39) | RECQLMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7373171 | 0.90 | AVPR2 (0.49) | RECQLMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7371835 | 0.89 | AVPR1A (0.47) | MEN1KMT2ASMN1; SMN2AVPR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |