Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7370882 | 0.99 | PDE2A (0.55) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7376624 | 0.90 | CYP11B1 (0.50) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7371110 | 0.89 | PDGFRB (0.46) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7374146 | 0.88 | PDGFRB (0.43) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7370258 | 0.87 | MKNK1 (0.46) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7365284 | 0.87 | PDGFRB (0.51) | CYP3A4CYP1A1CYP1A2CYP1B1CYP11B2 | |
| SCHEMBL7373044 | 0.87 | CYP11B1 (0.49) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL20445308 | 0.87 | PDE2A (0.55) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7372367 | 0.86 | CYP11B2 (0.45) | CYP3A4CYP1A1CYP1A2CYP1B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL23736209 | 0.85 | PDE2A (0.54) | PDE2ACYP3A4CYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |