Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371608 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL | |
| SCHEMBL7374292 | 0.92 | RECQL (0.40) | ALDH1A1MAPTSMN1; SMN2RECQLMAPK1 | |
| SCHEMBL7374290 | 0.92 | RECQL (0.40) | ALDH1A1MAPTSMN1; SMN2RECQLMAPK1 | |
| SCHEMBL7378362 | 0.92 | PPARD (0.45) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL | |
| SCHEMBL7378365 | 0.92 | PPARD (0.45) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL | |
| SCHEMBL7374038 | 0.88 | RECQL (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL | |
| SCHEMBL7372350 | 0.87 | AVPR2 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL | |
| SCHEMBL7372435 | 0.86 | RECQL (0.46) | ALDH1A1MAPTSMN1; SMN2RECQLMAPK1 | |
| SCHEMBL7368652 | 0.86 | RECQL (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL | |
| SCHEMBL7374760 | 0.86 | AVPR2 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |