Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 20/20 | 0.49 |
| ▸ | PLG | P00747 | 8/20 | 0.43 |
| ▸ | PLAT | P00750 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437735 | 0.91 | PLAU (0.61) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6993335 | 0.90 | PLAU (0.60) | PLAUPLGPLAT | |
| SCHEMBL6439174 | 0.86 | PLAU (0.44) | PLAUPLGPLAT | |
| SCHEMBL6434509 | 0.84 | PLAU (0.65) | PLAU | |
| Hydrochloric Acid SCHEMBL6990751 | 0.83 | PLAU (0.64) | PLAU | |
| SCHEMBL6437720 | 0.81 | PLAU (0.67) | PLAUPLGPLAT | |
| SCHEMBL6437267 | 0.81 | PLAU (0.69) | PLAUPLGPLAT | |
| SCHEMBL6438379 | 0.81 | PLAU (0.67) | PLAUPLAT | |
| Hydrochloric Acid SCHEMBL6995674 | 0.81 | PLAU (0.66) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6432705 | 0.81 | PLAU (0.59) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |
| EP-1077945-A1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000005214-A2 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2000-02-03 | — | — | WO | disclosed |