⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374701 | 0.83 | — | — | |
| SCHEMBL10923490 | 0.81 | — | — | |
| SCHEMBL683233 | 0.81 | — | — | |
| SCHEMBL11372603 | 0.80 | — | — | |
| SCHEMBL11366760 | 0.80 | — | — | |
| SCHEMBL11365002 | 0.78 | — | — | |
| SCHEMBL11384808 | 0.73 | — | — | |
| SCHEMBL11375733 | 0.71 | — | — | |
| SCHEMBL11376807 | 0.70 | — | — | |
| SCHEMBL7347033 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588734-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORP. (US) | 1986-05-13 | — | — | US | disclosed |
| US-4565825-A | Antihypertensive N-benzimidazolyl- and N-imidazolyl-amino acid derivatives | USV PHARMACEUTICAL CORP. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4548928-A | ANGIOTENSIN INHIBITORS | USV PHARMACEUTICAL CO. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4507312-A | Antihypertensive amides | USV PHARMACEUTICAL CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4304771-A | N-SULFUR-CONTAINING HETEROCYCLE SUBSTITUTED | USV PHARMACEUTICAL CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |
| US-4256761-A | Antihypertensive amides | USV PHARMACEUTICAL CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |