Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 9/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 9/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601350 | 0.70 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1PMP22 | |
| SCHEMBL8861405 | 0.70 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1GLO1 | |
| SCHEMBL8861403 | 0.70 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1GLO1 | |
| Valine SCHEMBL5728230 | 0.70 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1GLO1 | |
| SCHEMBL25268703 | 0.69 | SLC1A3 (0.32) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25263200 | 0.69 | SLC1A3 (0.32) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL400832 | 0.69 | TP53 (0.36) | SLC7A5 | |
| SCHEMBL600021 | 0.64 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL1007447 | 0.64 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL468084 | 0.64 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |
| EP-0730590-B1 | ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | DU PONT PHARM CO (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0970950-A2 | Novel isoxazoline and isoxazole fibrinogen receptor antagonists | DuPont Pharmaceuticals Company (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1995014683-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-06-01 | — | — | WO | disclosed |