SCHEMBL737305

SCHEMBL737305

O=C(O)c1cc(Cl)c(O)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 1.00
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
CA14 Q9ULX7 3/20 0.56
TPMT P51580 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HSD17B10 Q99714 2/20 0.56
CA3 P07451 2/20 0.56
CA4 P22748 2/20 0.56
CA6 P23280 2/20 0.56
CA5A P35218 2/20 0.56
CA5B Q9Y2D0 2/20 0.56
DPP4 P27487 2/20 0.56
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
MAPT P10636 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28853691 0.97 TTR (0.95) TTRCA12CA1CA2CA7
SCHEMBL30689081 0.88 TTR (0.78) TTRCA12CA1CA2CA7
SCHEMBL1458206 0.88 TTR (0.78) TTRCA12CA1CA2CA7
SCHEMBL11556678 0.86 TTR (0.76) TTRCA12CA1CA2CA7
SCHEMBL2684340 0.84 TTR (0.72) TTRCA12CA1CA2CA7
SCHEMBL983707 0.84 TTR (0.72) TTRCA12CA1CA2CA7
SCHEMBL987210 0.84 TTR (0.72) TTRCA12CA1CA2CA7
SCHEMBL26653812 0.84 TTR (0.72) TTRCA12CA1CA2CA7
SCHEMBL3777696 0.84 TTR (0.72) TTRCA12CA1CA2CA7
SCHEMBL29998931 0.84 TTR (0.72) TTRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591561-A Multi-tenor Synthesis method of thunder 上海药坦药物研究开发有限公司 2025-03-11 CN claimed
CN-118638276-A Carboxylic acid water reducing agent mother liquor and preparation method thereof 重庆市潼南区富景新材料科技有限公司 2024-09-13 CN claimed
CN-118240476-A Multi-resin-based high-performance heat dissipation coating and preparation method thereof 汇聚精密科技股份有限公司 2024-06-25 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-113816940-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-21 CN claimed
CN-113754634-A Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2021-12-07 CN claimed
CN-112500281-A Preparation method of syringic acid 唐山师范学院 2021-03-16 CN claimed
CN-111793039-A Preparation method of dortinode 苏州明锐医药科技有限公司 2020-10-20 CN claimed
CN-111662247-A Synthesis method of dortinode 苏州明锐医药科技有限公司 2020-09-15 CN claimed
CN-107523580-B Halogenated p-hydroxybenzoic acid oxidative decarboxylase gene odcA and application thereof 南京农业大学 2020-06-09 CN claimed
US-4923947-A Thermotropic liquid crystalline aromatic polyesters of disubstituted 4,4'-dihydroxydiphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
US-4923955-A Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
EP-0358147-A2 Thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-03-14 EP claimed
US-4874800-A BLENDED WITH POLYAMIDE TREATED FILLER; HIGH STRENGTH, HEAT RESISTANCE POLYPLASTICS CO., LTD. (JP) 1989-10-17 US claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP claimed
EP-0321107-A1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-21 EP claimed
US-4737398-A POLYAZOMETHYNE, POLYESTER OR POLYCARBONATE POLYPLASTICS CO., LTD. (JP) 1988-04-12 US claimed
US-4726998-A LIQUID CRYSTAL POLYMER SUBSTRATE, MAGNETIC LAYER POLYPLASTICS CO., LTD. (JP) 1988-02-23 US claimed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed