Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737305 | 0.84 | TTR (1.00) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL1114408 | 0.84 | TTR (1.00) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL11184770 | 0.83 | TTR (0.48) | TTRTSHRALDH1A1MAPTHSD17B10 | |
| Bromide SCHEMBL28853691 | 0.82 | TTR (0.95) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL1879399 | 0.82 | TTR (0.47) | TTRCA5AALDH1A1LMNAMAPT | |
| SCHEMBL15796379 | 0.81 | TTR (0.56) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL8380493 | 0.79 | TTR (0.54) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL30689081 | 0.78 | TTR (0.78) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL1458206 | 0.78 | TTR (0.78) | TTRTSHRTPMTCA12CA1 | |
| SCHEMBL29373087 | 0.78 | TTR (0.78) | TTRTPMTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636637-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | Forma Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| CN-106124646-A | A kind of detect the method for polarity phenol chloro/bromo disinfection byproduct (DBP) in water | 南京大学 | 2016-11-16 | — | — | CN | disclosed |
| US-7875631-B2 | e.g.1-(3,5-dichlorophenyl)-2-formyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; to prevent and/or treat cancer and other abnormal cell growth, and metabolic as well as blood vessel proliferate disorders, in which uncontrolled expression of insulin-like growth factor-1 receptor is observed | ANALYTECON S.A. (CH) | 2011-01-25 | — | — | US | disclosed |
| US-4400387-A | USEFUL IN VETERINARY MEDICINE FOR TREATMENT OF PSYCHOLOGICAL DISORDERS | S. A. LABAZ-SANOFI N.V. (FR) | 1983-08-23 | — | — | US | disclosed |