SCHEMBL7374157

SCHEMBL7374157

Nc1c(C(Cc2ccc3cncnc3c2)N2CCNCC2=O)ccc2sc(Cl)cc12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7409252 0.74 F10 (0.32) F10
SCHEMBL7407923 0.72 EGFR (0.36)
SCHEMBL7451661 0.71 F10 (0.46) F10
SCHEMBL7370636 0.71 F10 (0.40) F10
SCHEMBL7370841 0.71
SCHEMBL7375611 0.70 CDK2 (0.31)
SCHEMBL7372560 0.69 F10 (0.42) F10
SCHEMBL7406755 0.68 F10 (0.40) F10
SCHEMBL7407384 0.68 P2RX7 (0.33)
SCHEMBL7553322 0.67 F10 (0.44) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051176-A4 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARM PROD INC (US) 2002-06-12 EP disclosed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed