Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291214 | 0.91 | SYK (0.43) | SYKMEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL9813956 | 0.86 | HTT (0.49) | MEN1KMT2AITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL328631 | 0.82 | SYK (0.49) | SYKMEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL16281851 | 0.82 | SYK (0.49) | SYKMEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL7367330 | 0.80 | SYK (0.47) | SYKMEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL22829843 | 0.79 | HTT (0.47) | SYKMEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL26192488 | 0.78 | SYK (0.46) | SYKMEN1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL7290272 | 0.78 | MME (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL4632517 | 0.78 | SYK (0.53) | SYKMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL4632514 | 0.78 | SYK (0.53) | SYKMEN1KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341081-B1 | Novel amino acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5317021-A | Analgesics, anticonvulsants | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-05-31 | — | — | US | disclosed |
| US-5202340-A | Analgesics, anticonvulsants, anxiolytic agents, inhibitors for enkephalinases | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |