Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376303 | 1.00 | CA12 (0.39) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL17860834 | 0.89 | CA12 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL8353290 | 0.89 | CA12 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL27711551 | 0.78 | MEN1 (0.45) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL7416221 | 0.77 | CYP1A2 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL8127521 | 0.77 | CYP1A2 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL7416225 | 0.77 | CYP1A2 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2837530 | 0.77 | MEN1 (0.44) | CA12CA1CA2CA9MEN1 | |
| Hydrochloric Acid SCHEMBL3894157 | 0.77 | MEN1 (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL1854219 | 0.77 | MEN1 (0.44) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018111-A1 | COMPOUNDS CONTAINING BASIC AND ACIDIC TERMINI USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |