Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416225 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19HTTSYK | |
| SCHEMBL8127521 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19HTTSYK | |
| SCHEMBL23489251 | 0.90 | ALDH1A1 (0.42) | CYP1A2CYP2C9CYP2C19HTTSYK | |
| SCHEMBL27711551 | 0.88 | MEN1 (0.45) | SYKMEN1KMT2AGAATDP1 | |
| SCHEMBL2837530 | 0.86 | MEN1 (0.44) | SYKMEN1KMT2AGAATDP1 | |
| Hydrochloric Acid SCHEMBL3894157 | 0.86 | MEN1 (0.44) | SYKMEN1KMT2AGAATDP1 | |
| SCHEMBL1854219 | 0.86 | MEN1 (0.44) | SYKMEN1KMT2AGAATDP1 | |
| SCHEMBL584353 | 0.86 | MEN1 (0.44) | SYKMEN1KMT2AGAATDP1 | |
| Hydrochloric Acid SCHEMBL2681080 | 0.85 | MEN1 (0.42) | SYKMEN1KMT2AGAATDP1 | |
| Hydrochloric Acid SCHEMBL23575089 | 0.85 | MEN1 (0.42) | SYKMEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821241-A | INHIBIT BINDING OF FIBRINOGEN TO BLOOD PLATELETS, INHIBIT AGGREGATION OF BLOOD PLATELETS, PREVENT OR TREAT THROMBUS OR EMBOLUS FORMATION | MERCK & CO., INC. (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0684823-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1997-07-09 | — | — | EP | disclosed |
| EP-0684823-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |