Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374195 | 0.80 | ACHE (0.49) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL1063008 | 0.78 | MAPK14 (0.69) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL5374680 | 0.75 | ACHE (0.56) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL1059207 | 0.73 | MAPK14 (0.61) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL5371606 | 0.70 | ACHE (0.48) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL5369588 | 0.70 | ACHE (0.49) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL14559817 | 0.69 | MAPK14 (0.63) | GRIN1MAPK14GRIN2BMEN1KMT2A | |
| SCHEMBL5377846 | 0.69 | ACHE (0.53) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL5371601 | 0.69 | ACHE (0.50) | ACHEHTR4SIGMAR1GRIN1CHRM2 | |
| SCHEMBL1063085 | 0.68 | CCR3 (0.72) | ACHEHTR4SIGMAR1CHRM2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080078-A1 | HETEROCYCLIC COMPOUNDS AND METHODS TO TREAT CARDIAC FAILURE AND OTHER DISORDERS | SCIOS INC. (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061426-A1 | HETEROCYCLIC COMPOUNDS AND METHODS TO TREAT CARDIAC FAILURE AND OTHER DISORDERS | SCIOS INC. (US) | 1999-12-02 | — | — | WO | disclosed |