Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 13/20 | 0.56 |
| ▸ | MMP13 | P45452 | 6/20 | 0.56 |
| ▸ | MMP1 | P03956 | 4/20 | 0.56 |
| ▸ | MMP3 | P08254 | 3/20 | 0.56 |
| ▸ | MMP9 | P14780 | 12/20 | 0.54 |
| ▸ | MMP7 | P09237 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7653125 | 0.93 | SLC1A3 (0.53) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL16005166 | 0.86 | MMP2 (0.61) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL28042871 | 0.86 | MMP2 (0.61) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL6500230 | 0.85 | MMP2 (0.61) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL383079 | 0.85 | MMP2 (0.61) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL3861153 | 0.84 | MMP2 (0.53) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL7370003 | 0.84 | MMP2 (0.72) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL4041728 | 0.84 | TDP1 (0.63) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL2219245 | 0.84 | MMP2 (0.56) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL14608753 | 0.84 | MMP2 (0.53) | MMP2MMP13MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098889-A1 | SUBSTITUTED PIPERAZONES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004001-A1 | SUBSTITUTED PIPERAZONES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |