Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986818 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL738198 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7283999 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL3054776 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL13912231 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL2115037 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL762984 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL5778346 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL27548005 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL9036055 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMCYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383635-A2 | Peptides having renin inhibitory activity their preparation and use | Sankyo Company Limited (JP) | 1990-08-22 | — | — | EP | disclosed |
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |