Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31368699 | 0.87 | HTR3A (0.49) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL7279216 | 0.84 | HTR3A (0.55) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL7281271 | 0.84 | HTR3A (0.71) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL31368701 | 0.84 | HTR3A (0.55) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL7290934 | 0.84 | HTR3A (0.55) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Hydrochloric Acid SCHEMBL7288488 | 0.83 | HTR3A (0.70) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL7287927 | 0.82 | HTR2A (0.72) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| Hydrochloric Acid SCHEMBL10428107 | 0.82 | HTR3A (0.71) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL31368691 | 0.81 | HTR3A (0.49) | HTR3AHTR2ASLC6A4HRH1PDE4D | |
| SCHEMBL7287895 | 0.77 | HTR3A (0.55) | HTR3AHTR2ASLC6A4HRH1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |