Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.46 |
| ▸ | ITGAV | P06756 | 9/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514763 | 0.93 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL7514754 | 0.93 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6419571 | 0.80 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2785184 | 0.79 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL2784510 | 0.79 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6418707 | 0.79 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL7402755 | 0.78 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL7402752 | 0.78 | ITGB3 (0.74) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6418531 | 0.78 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5ITGB1 | |
| SCHEMBL6418535 | 0.78 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023073-A1 | VITRONECTIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999015178-A1 | VITRONECTIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | disclosed |