Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30926677 | 0.85 | KMT2A (0.73) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27180940 | 0.85 | KMT2A (0.73) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL30702318 | 0.81 | PFKFB3 (0.76) | MEN1KMT2AAKR1C3GFERHDAC2 | |
| SCHEMBL4063367 | 0.81 | PFKFB3 (0.76) | MEN1KMT2AAKR1C3GFERHDAC2 | |
| SCHEMBL30702319 | 0.81 | PFKFB3 (0.76) | MEN1KMT2AAKR1C3GFERHDAC2 | |
| SCHEMBL14659760 | 0.81 | MEN1 (0.65) | MEN1KMT2AAKR1C3ALDH1A1GFER | |
| SCHEMBL14423923 | 0.80 | AKR1C3 (0.58) | MEN1KMT2AAKR1C3ALDH1A1L3MBTL1 | |
| SCHEMBL14680112 | 0.79 | KMT2A (0.60) | MEN1KMT2AAKR1C3ALDH1A1L3MBTL1 | |
| SCHEMBL7366821 | 0.79 | AKR1C3 (0.67) | MEN1KMT2AAKR1C3GFERHDAC2 | |
| SCHEMBL4253424 | 0.79 | MEN1 (0.79) | MEN1KMT2ARAB9AAKR1C3GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |