Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063367 | 0.81 | PFKFB3 (0.76) | AKR1C3MEN1KMT2AGFERMAPT | |
| SCHEMBL30702319 | 0.81 | PFKFB3 (0.76) | AKR1C3MEN1KMT2AGFERMAPT | |
| SCHEMBL30702318 | 0.81 | PFKFB3 (0.76) | AKR1C3MEN1KMT2AGFERMAPT | |
| SCHEMBL7375504 | 0.80 | MEN1 (0.65) | AKR1C3MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14680112 | 0.79 | KMT2A (0.60) | AKR1C3MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4253424 | 0.79 | MEN1 (0.79) | AKR1C3MEN1KMT2AGFERMAPT | |
| SCHEMBL7366821 | 0.79 | AKR1C3 (0.67) | AKR1C3MEN1KMT2AGFERMAPT | |
| SCHEMBL14659760 | 0.78 | MEN1 (0.65) | AKR1C3MEN1KMT2AALDH1A1GFER | |
| SCHEMBL14423939 | 0.76 | HDAC1 (0.44) | MEN1KMT2AALDH1A1MAPTHDAC2 | |
| SCHEMBL16020318 | 0.76 | AKR1C3 (0.53) | AKR1C3MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |