Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377774 | 0.88 | AKT1 (0.41) | MAPK1AKT1KMT2AMEN1 | |
| SCHEMBL7360266 | 0.72 | SMN1; SMN2 (0.42) | AKT1KMT2AMEN1 | |
| SCHEMBL5756624 | 0.69 | KDR (0.54) | MAPK1AKT1KMT2AMEN1NR3C1 | |
| SCHEMBL6376557 | 0.67 | AKT1 (0.48) | MAPK1AKT1SLC6A4FFAR2 | |
| SCHEMBL7376714 | 0.67 | TRPV1 (0.48) | JAK1MAPK1 | |
| SCHEMBL6376191 | 0.66 | AKT1 (0.48) | MAPK1AKT1KMT2AMEN1SLC6A4 | |
| SCHEMBL7380430 | 0.66 | SLC6A4 (0.38) | AKT1SLC6A4 | |
| SCHEMBL6806957 | 0.65 | AKT1 (0.50) | MAPK1AKT1SLC6A4FFAR2 | |
| SCHEMBL19555627 | 0.64 | EPHX2 (0.59) | KMT2A | |
| SCHEMBL10460532 | 0.64 | SLC6A4 (0.55) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |