Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415440 | 0.79 | F10 (0.49) | SMN1; SMN2NPC1ALOX15HTTRAB9A | |
| SCHEMBL6413590 | 0.76 | AKT1 (0.45) | F10AKT1 | |
| Hydrochloric Acid SCHEMBL7455665 | 0.74 | AKT1 (0.47) | SMN1; SMN2NPC1ALOX15HTTRAB9A | |
| SCHEMBL7447691 | 0.73 | AKT1 (0.46) | SMN1; SMN2ALOX15RAB9AF10AKT1 | |
| Hydrochloric Acid SCHEMBL6710608 | 0.73 | NPC1 (0.53) | SMN1; SMN2NPC1ALOX15HTTRAB9A | |
| SCHEMBL6714678 | 0.73 | NPC1 (0.53) | SMN1; SMN2NPC1ALOX15HTTRAB9A | |
| SCHEMBL7375515 | 0.72 | JAK1 (0.42) | KMT2AMEN1AKT1 | |
| Hydrochloric Acid SCHEMBL7448873 | 0.71 | NPC1 (0.46) | SMN1; SMN2NPC1ALOX15HTTRAB9A | |
| Hydrochloric Acid SCHEMBL7444958 | 0.71 | NPC1 (0.46) | SMN1; SMN2NPC1ALOX15HTTRAB9A | |
| SCHEMBL7365896 | 0.71 | F10 (0.52) | SMN1; SMN2NPC1ALOX15HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |