Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MME | P08473 | 5/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003020 | 0.77 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL91080 | 0.77 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL1134239 | 0.77 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL29365197 | 0.77 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL29495388 | 0.77 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL926388 | 0.77 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| Water SCHEMBL27677887 | 0.76 | GAA (0.90) | GAAMAPTMMEACESMYD3 | |
| Hydrochloric Acid SCHEMBL2521110 | 0.75 | GAA (0.96) | GAAMAPTMMEACESMYD3 | |
| Hydrochloric Acid SCHEMBL2521107 | 0.75 | GAA (0.96) | GAAMAPTMMEACESMYD3 | |
| Hydrochloric Acid SCHEMBL4649258 | 0.75 | GAA (0.96) | GAAMAPTMMEACESMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793674-B1 | HUMAN NEUTROPHIL ELASTASE INHIBITORS | CORTECH INC (US) | 2000-05-24 | — | — | EP | claimed |
| EP-0793674-A1 | HUMAN NEUTROPHIL ELASTASE INHIBITORS | CORTECH, INC. (US) | 1997-09-10 | — | — | EP | claimed |
| WO-1996016080-A1 | HUMAN NEUTROPHIL ELASTASE INHIBITORS | CORTECH, INC. (US) | 1996-05-30 | — | — | WO | claimed |