Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | MME | P08473 | 6/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365197 | 1.00 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL1134239 | 1.00 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL91080 | 1.00 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL29495388 | 1.00 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL14003020 | 1.00 | GAA (1.00) | GAAMAPTMMEACESMYD3 | |
| Hydrochloric Acid SCHEMBL2521107 | 0.98 | GAA (0.96) | GAAMAPTMMEACESMYD3 | |
| SCHEMBL27571214 | 0.98 | GAA (0.96) | GAAMAPTMMEACESMYD3 | |
| Hydrochloric Acid SCHEMBL2521110 | 0.98 | GAA (0.96) | GAAMAPTMMEACESMYD3 | |
| Hydrochloric Acid SCHEMBL4649258 | 0.98 | GAA (0.96) | GAAMAPTMMEACESMYD3 | |
| Methyl Alcohol SCHEMBL27493922 | 0.96 | GAA (0.93) | GAAMAPTMMEACESMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| US-12240808-B2 | Process for the synthesis of calebin-a and its intermediates | MAJEED MUHAMMED (IN) | 2025-03-04 | — | — | US | claimed |
| US-20240360177-A1 | PEPTIDES WITH ANTIMICROBIAL ACTIVITIES | AIMMAX THERAPEUTICS, INC. | 2024-10-31 | — | — | US | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| EP-4396196-A1 | PEPTIDES WITH ANTIMICROBIAL ACTIVITIES | Aimmax Therapeutics, Inc. (US) | 2024-07-10 | — | — | EP | claimed |
| EP-4377291-A2 | PROCESS FOR THE SYNTHESIS OF CALEBIN-A AND ITS INTERMEDIATES | Majeed, Muhammed (IN) | 2024-06-05 | — | — | EP | claimed |
| CN-117897394-A | Peptides with antimicrobial activity | 美商安满药物开发公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117586170-B | Indolinyl acyl derivative and synthetic method of isoquinoline formyl derivative | 江苏集萃分子工程研究院有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117586170-A | Indolinyl acyl derivative and synthetic method of isoquinoline formyl derivative | 江苏集萃分子工程研究院有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-116655519-A | Asymmetric chiral conversion method of S- (-) -indoline-2-carboxylic acid | 上海吉奉生物科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| EP-0308341-B1 | PROCESS FOR THE INDUSTRIAL SYNTHESIS OF PERINDOPRIL AND FOR ITS PRINCIPAL SYNTHESIS INTERMEDIATES | ADIR ET COMPAGNIE (FR) | 1990-12-12 | — | — | EP | claimed |
| US-4954640-A | Alpha-methyl benzyl amine salt of indoline -2- carboxylic acid | ADIR ET CIE (FR) | 1990-09-04 | — | — | US | claimed |
| US-4935525-A | Process for the industrial synthesis of (2S, 3aS, 7aS) 2-carboxy perhydroindole, application to the industrial synthesis of carboxyalkyl dipeptides | ADIR ET CIE (FR) | 1990-06-19 | — | — | US | claimed |
| US-4898822-A | Process for preparing optically active indoline-2-carboxylic acid | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-02-06 | — | — | US | claimed |
| EP-0197474-A2 | Process for preparing optically active indoline-2-carboxylic acid | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-10-15 | — | — | EP | claimed |
| US-4614806-A | Process for the asymmetric synthesis of chiral indoline-2-carboxylic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-09-30 | — | — | US | claimed |
| US-4595766-A | Process for the preparation of an indoline carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1986-06-17 | — | — | US | claimed |
| US-4479963-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | claimed |
| US-4374847-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-02-22 | — | — | US | claimed |
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360177-A1 | PEPTIDES WITH ANTIMICROBIAL ACTIVITIES | VIP, FPR2, FPR1 | GAA 2779/4885MAPT 4735/4885MME 568/4885 |
| US-12240808-B2 | Process for the synthesis of calebin-a and its intermediates | TFEB, CALD1, CALR | GAA 1566/4885MAPT 1961/4885MME 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.