Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.53 |
| ▸ | CTSL | P07711 | 8/20 | 0.50 |
| ▸ | CTSS | P25774 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341638 | 0.91 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27492433 | 0.91 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27472820 | 0.88 | CTSK (0.49) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL7448242 | 0.88 | CTSK (0.49) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL7346145 | 0.84 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| Hydrochloric Acid SCHEMBL7337310 | 0.80 | CTSK (0.47) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL7450915 | 0.80 | CTSK (0.60) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL6581062 | 0.78 | CTSK (0.72) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580230 | 0.78 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27483446 | 0.78 | CTSK (0.60) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016177-A9 | METHOD OF INHIBITING CATHEPSIN K | — | 1997-07-24 | — | — | WO | disclosed |