Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 10/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.51 |
| ▸ | PDE4A | P27815 | 8/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468632 | 1.00 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL7468624 | 1.00 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL7465654 | 0.84 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL7465642 | 0.84 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL7464347 | 0.80 | TNFRSF1A (0.48) | — | |
| SCHEMBL7464113 | 0.80 | TNFRSF1A (0.48) | — | |
| SCHEMBL7464120 | 0.80 | TNFRSF1A (0.48) | — | |
| SCHEMBL7384149 | 0.77 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL7384154 | 0.77 | PDE4B (0.47) | PDE4DPDE4BPDE4APDE4CPDE5A | |
| SCHEMBL7379306 | 0.75 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889879-A1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997036864-A1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |