Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452332 | 0.85 | PPARG (0.63) | LMNAPPARGHDAC6SENP1 | |
| SCHEMBL7856525 | 0.84 | PPARG (0.59) | LMNAPPARGHDAC6SENP1 | |
| SCHEMBL7372217 | 0.83 | PPARG (0.48) | BCHEMAPTLMNASMN1; SMN2PPARG | |
| SCHEMBL7377637 | 0.83 | MAPT (0.55) | BCHEMAPTLMNASMN1; SMN2PPARG | |
| SCHEMBL8500043 | 0.83 | MAPT (0.57) | BCHEMAPTLMNASMN1; SMN2PPARG | |
| SCHEMBL7380126 | 0.82 | ITGB3 (0.53) | SMN1; SMN2 | |
| SCHEMBL7373860 | 0.81 | PTGER1 (0.44) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL8496894 | 0.81 | MAPT (0.55) | BCHEMAPTLMNASMN1; SMN2PPARG | |
| SCHEMBL7379916 | 0.81 | PPARG (0.51) | LMNASMN1; SMN2PPARGHDAC6 | |
| SCHEMBL7380550 | 0.81 | ITGB3 (0.43) | BCHEMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | claimed |