Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374132 | 0.88 | DPP4 (0.33) | SLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL7412948 | 0.88 | DPP4 (0.33) | SLC1A3SLC1A2SLC1A1DPP4CTSL | |
| SCHEMBL7383092 | 0.72 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7372843 | 0.67 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7382436 | 0.67 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29052877 | 0.67 | METAP2 (0.39) | SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL29052876 | 0.67 | METAP2 (0.39) | SLC1A3SLC1A2SLC1A1CTSK | |
| SCHEMBL7414748 | 0.66 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1CTSLCTSB | |
| SCHEMBL7372849 | 0.64 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23849174 | 0.64 | METAP2 (0.42) | SLC1A3SLC1A2SLC1A1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922054-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997046576-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |