Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602589 | 0.94 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL7604426 | 0.94 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL5988339 | 0.94 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL28404629 | 0.85 | ALDH1A1 (0.60) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL15635452 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL8452666 | 0.83 | TSHR (0.46) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL9407076 | 0.81 | TSHR (0.44) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL8823319 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL18256779 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10SOAT1TSHR | |
| SCHEMBL14504458 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10SOAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914158-A2 | PHARMACEUTICAL COMBINATION CONTAINING A COMPOUND HAVING ANGIOTENSIN II AND ANTAGONISTIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997037688-A2 | PHARMACEUTICAL COMBINATION CONTAINING A COMPOUND HAVING ANGIOTENSIN II AND ANTAGONISTIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-16 | — | — | WO | disclosed |