Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 20/20 | 0.52 |
| ▸ | PLG | P00747 | 10/20 | 0.42 |
| ▸ | PLAT | P00750 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435153 | 1.00 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL6434680 | 1.00 | PLAU (0.52) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL6433474 | 0.99 | PLAU (0.51) | PLAUPLGPLAT | |
| Bicarbonate SCHEMBL6964761 | 0.86 | PLAU (0.64) | PLAUPLGPLAT | |
| SCHEMBL6437267 | 0.85 | PLAU (0.69) | PLAUPLGPLAT | |
| SCHEMBL6433793 | 0.85 | PLAU (0.53) | PLAUPLGPLAT | |
| SCHEMBL6433783 | 0.85 | PLAU (0.53) | PLAUPLGPLAT | |
| SCHEMBL6433788 | 0.85 | PLAU (0.53) | PLAUPLGPLAT | |
| Bicarbonate SCHEMBL6969353 | 0.85 | PLAU (0.63) | PLAUPLGPLAT | |
| SCHEMBL6433537 | 0.83 | PLAU (0.56) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077945-A1 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000005214-A2 | ISOQUINOLINES AS UROKINASE INHIBITORS | PFIZER INC. (US) | 2000-02-03 | — | — | WO | disclosed |