SCHEMBL7378587

SCHEMBL7378587

Nc1ncnc2cc(C[C@]3([N]S(=O)(=O)C=Cc4ccc(Cl)s4)CCNC3=O)ccc12

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 11/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589134 0.84 F10 (0.34) F10
SCHEMBL7376654 0.77 F10 (0.33) F10
Trifluoroacetic Acid SCHEMBL7373181 0.73 F10 (0.33) F10
Trifluoroacetic Acid SCHEMBL7374544 0.73 F10 (0.33) F10
SCHEMBL7459487 0.70 F10 (0.34) F10
SCHEMBL1654343 0.69 F10 (0.60) F10
SCHEMBL1654344 0.69 F10 (0.60) F10
SCHEMBL7377585 0.69 F10 (0.38) F10
SCHEMBL6220812 0.68 F10 (0.51) F10
SCHEMBL4388530 0.68 F10 (0.46) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed