SCHEMBL7589134

SCHEMBL7589134

Nc1ncnc2cc(C[C@]3([N]C(=O)C=Cc4ccc(Cl)s4)CCNC3=O)ccc12

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7378587 0.84 F10 (0.35) F10
SCHEMBL7376654 0.83 F10 (0.33) F10
Trifluoroacetic Acid SCHEMBL7373181 0.79 F10 (0.33) F10
Trifluoroacetic Acid SCHEMBL7374544 0.79 F10 (0.33) F10
SCHEMBL7459487 0.73 F10 (0.34) F10
SCHEMBL7372777 0.72 F10 (0.43) F10
Trifluoroacetic Acid SCHEMBL7378536 0.70 F10 (0.33) F10
SCHEMBL1652496 0.69 F10 (0.53) F10
SCHEMBL4385765 0.69 F10 (0.53) F10
SCHEMBL1652838 0.69 F10 (0.43) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP claimed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP claimed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO claimed