Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377871 | 0.87 | PTGS1 (0.40) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7389627 | 0.84 | CYP19A1 (0.42) | TSHR | |
| SCHEMBL7385948 | 0.83 | CYP19A1 (0.41) | FAAH | |
| SCHEMBL7378937 | 0.73 | KCNQ2 (0.40) | LMNANFKB1TSHRBLMCHRM1 | |
| SCHEMBL9206348 | 0.72 | TYR (0.46) | PTGS1 | |
| SCHEMBL11574439 | 0.72 | PTGS2 (0.55) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7383042 | 0.72 | CHRM2 (0.42) | AKR1C3HTR2AAKR1C2EPHX1 | |
| SCHEMBL9111108 | 0.72 | PTGS2 (0.68) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL13143747 | 0.72 | PTGS2 (0.55) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL12896272 | 0.71 | PTGS2 (0.66) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |