Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 9/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669630 | 0.91 | RXFP1 (0.40) | RXFP1CCR2PPARGPPARAKCNQ4 | |
| SCHEMBL7669626 | 0.91 | RXFP1 (0.40) | RXFP1CCR2PPARGPPARAKCNQ4 | |
| SCHEMBL7513228 | 0.83 | RXFP1 (0.42) | RXFP1CCR2PPARGPPARAKCNQ4 | |
| SCHEMBL7667429 | 0.79 | ALDH1A1 (0.47) | RXFP1CCR2PPARGPPARACYP1A2 | |
| SCHEMBL7387757 | 0.78 | RXFP1 (0.45) | RXFP1CCR2PPARGPPARAKCNQ4 | |
| SCHEMBL7673407 | 0.76 | RXFP1 (0.43) | RXFP1CCR2PPARGPPARACYP1A2 | |
| SCHEMBL7379048 | 0.76 | RXFP1 (0.43) | RXFP1CCR2PPARGPPARACYP1A2 | |
| SCHEMBL7379044 | 0.76 | RXFP1 (0.43) | RXFP1CCR2PPARGPPARACYP1A2 | |
| SCHEMBL6755116 | 0.76 | RXFP1 (0.41) | RXFP1CCR2KCNQ4KCNQ5CYP1A2 | |
| SCHEMBL6755114 | 0.76 | RXFP1 (0.41) | RXFP1CCR2KCNQ4KCNQ5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000067-B1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-10-23 | — | — | EP | disclosed |
| EP-1000067-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005147-A1 | THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1999-02-04 | — | — | WO | disclosed |