Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.66 |
| ▸ | HTR2B | P41595 | 17/20 | 0.66 |
| ▸ | HTR2A | P28223 | 16/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082972 | 0.95 | HTR2C (0.72) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7042913 | 0.86 | HTR2C (0.77) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7408043 | 0.85 | HTR2C (0.91) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL15628396 | 0.81 | HTR2C (0.69) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7084100 | 0.81 | HTR2C (0.78) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7082946 | 0.80 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7405449 | 0.79 | HTR2C (0.69) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7374582 | 0.79 | HTR2C (0.68) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7078894 | 0.78 | HTR2C (1.00) | HTR2CHTR2BHTR2ACYP1A2 | |
| SCHEMBL7039791 | 0.78 | HTR2C (0.75) | HTR2CHTR2BHTR2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023783-A1 | INDOLE DERIVATIVES AS 5-HT RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM PLC (GB) | 1996-08-08 | — | — | WO | disclosed |