Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330265 | 1.00 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8330262 | 1.00 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7359794 | 0.88 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8475654 | 0.88 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7181002 | 0.84 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8332929 | 0.81 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7370981 | 0.81 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7370978 | 0.81 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7362543 | 0.81 | PDE4B (0.69) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL14456043 | 0.81 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869677-A | 3,3-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0796097-A4 | 3,3-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5719184-A | 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0796097-A1 | 3,3-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996019994-A1 | 3,3-(DISUBSTITUTED)CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |