Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.52 |
| ▸ | KDM4A | O75164 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7206017 | 0.85 | KDM4A (0.65) | SMN1; SMN2SIGMAR1TMEM97KDM4AKDM4C | |
| SCHEMBL40675 | 0.85 | KDM4A (0.66) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL5479984 | 0.84 | CARM1 (0.56) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL13359820 | 0.82 | CARM1 (0.59) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL5476106 | 0.81 | CARM1 (0.53) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL17974771 | 0.81 | CARM1 (0.53) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL7378382 | 0.81 | CARM1 (0.53) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL6338596 | 0.81 | KMT2A (0.77) | CARM1PRMT6PRMT8NPC1RAB9A | |
| SCHEMBL4805951 | 0.79 | CARM1 (0.51) | CARM1PRMT6PRMT8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5181661 | 0.79 | KMT2A (0.74) | CARM1PRMT6PRMT8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525478-A | Certain 4-aryl-1,4-dihydro-3,5-pyridinedicarboxylates having vasodilating and anti-hypertensive properties | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4370334-A | VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4338322-A | 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| US-4284634-A | HYPOTENSIVE VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4145432-A | 6-ACYLORYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND A METHOD OF EFFECTING VASODILATION THEREWITH | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |