Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5181661 | 0.98 | KMT2A (0.74) | KMT2ASMN1; SMN2THRATHRBCARM1 | |
| SCHEMBL11126800 | 0.97 | KMT2A (0.77) | KMT2ASMN1; SMN2THRATHRBCARM1 | |
| Hydrochloric Acid SCHEMBL11113894 | 0.95 | KMT2A (0.75) | KMT2ASMN1; SMN2THRATHRBCARM1 | |
| SCHEMBL13562531 | 0.91 | KMT2A (0.63) | KMT2ASMN1; SMN2THRATHRBCARM1 | |
| SCHEMBL4593680 | 0.90 | KMT2A (0.62) | KMT2ASMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL13562470 | 0.89 | KMT2A (0.61) | KMT2ASMN1; SMN2THRATHRBCARM1 | |
| SCHEMBL11982951 | 0.89 | KDM4A (0.60) | KMT2ASMN1; SMN2NPC1RAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL4786199 | 0.88 | TMEM97 (0.64) | KMT2ASMN1; SMN2THRATHRBEGFR | |
| SCHEMBL13562500 | 0.87 | ACHE (0.68) | KMT2AEGFRNPC1RAB9ATDP1 | |
| SCHEMBL13562515 | 0.87 | KMT2A (0.58) | KMT2ASMN1; SMN2THRATHRBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391070-B1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION YHTYMAE OY (FI) | 1994-01-19 | — | — | EP | claimed |
| US-5166437-A | Process for the preparation of fluoxetine | ORION-YHTYMA OY (FI) | 1992-11-24 | — | — | US | claimed |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-08-29 | — | — | US | disclosed |
| EP-4410772-A2 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | Infineum International Limited (GB) | 2024-08-07 | — | — | EP | disclosed |
| CN-118440229-A | Amine functional monomers and methods of making the same | 英菲诺姆国际有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-7709498-B2 | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-05-04 | — | — | US | disclosed |
| US-7709498-B2 | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-05-04 | — | — | US | disclosed |
| WO-2007009405-A1 | A METHOD FOR THE PREPARATION OF (R)-N-METHYL-3-(2-METHYLPHENOXY)-3-PHENYLPROPYLAMINE HYDROCHLORIDE (ATOMOXETINE) | ZENTIVA, A.S. (CZ) | 2007-01-25 | — | — | WO | disclosed |
| US-6838581-B2 | Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-01-04 | — | — | US | disclosed |
| US-20040110985-A1 | Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-06-10 | — | — | US | disclosed |
| EP-0929514-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS GYOGYSZERGYAR RT. (HU) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998011054-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS Gyógyszergyár Rt. (HU) | 1998-03-19 | — | — | WO | disclosed |
| EP-0391070-B1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION YHTYMAE OY (FI) | 1994-01-19 | — | — | EP | disclosed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110985-A1 | Process for the preparation of enantiomerically pure 3-phenyl-3-hydroxypropylamine | CYP2D6, ADH1A, TPH1 | KMT2A 1175/4885SMN1; SMN2 2307/4885THRA 3943/4885 |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | AMD1, HNMT, MAT1A | KMT2A 134/4885SMN1; SMN2 1268/4885THRA 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.