Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058748 | 0.89 | MAPT (0.34) | MAPKAPK2HDAC1 | |
| SCHEMBL7384137 | 0.85 | GRIN2B (0.34) | CPB2HDAC1 | |
| SCHEMBL6059200 | 0.80 | MAPT (0.35) | MAPKAPK2HDAC1 | |
| SCHEMBL6058746 | 0.78 | CYP17A1 (0.36) | MAPKAPK2HDAC1 | |
| SCHEMBL6058794 | 0.77 | GRIN2B (0.37) | HDAC1 | |
| SCHEMBL7382852 | 0.77 | — | — | |
| SCHEMBL6059026 | 0.76 | GRIN2B (0.37) | HDAC1 | |
| SCHEMBL6059388 | 0.75 | GRIN2B (0.39) | HDAC1 | |
| SCHEMBL6058911 | 0.75 | CYP17A1 (0.38) | HDAC1 | |
| SCHEMBL4007432 | 0.73 | CPB2 (0.52) | CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180098-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066557-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |