Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567884 | 0.89 | HTR2C (0.55) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5181381 | 0.89 | HTR2C (0.49) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13567861 | 0.88 | HTR2C (0.48) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13567885 | 0.88 | HTR2C (0.48) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7376563 | 0.87 | HTR2C (0.47) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13567860 | 0.87 | HTR2C (0.47) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19839017 | 0.86 | FKBP1A (0.50) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11104947 | 0.85 | HTR2C (0.52) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11104941 | 0.85 | HTR2C (0.52) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11109029 | 0.85 | HTR2C (0.52) | HTR2CAGTR2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057314-A | ANTICOAGULANTS | BIOCHEM PHARMA INC. (CA) | 2000-05-02 | — | — | US | disclosed |
| EP-0802916-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996019483-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-06-27 | — | — | WO | disclosed |