SCHEMBL738

SCHEMBL738

Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(O)O[C@H]3[C@H]2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 18/20 1.00
PDE3B Q13370 1/20 1.00
PDE3A Q14432 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12671632 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL17974376 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL12634565 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL17325408 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL12634582 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL18737202 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL24467522 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL21470181 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL21498373 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL14980248 1.00 STING1 (1.00) STING1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 59059 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436366-B1 None US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122094677-A Organic compound 2026-05-26 CN claimed
CN-122094676-A Organic compound 2026-05-26 CN claimed
CN-122067647-A Prediction and depth verification integration method for traditional Chinese medicine compound action mechanism research 国药集团德众(佛山)药业有限公司 2026-05-19 CN claimed
EP-4741012-A2 COMPOSITIONS AND METHODS FOR REDUCING AMYLOID BETA FORMATION AND COMPOSITION THEREFORE Aribio Co., Ltd. (KR) 2026-05-13 EP claimed
CN-117229211-B NO donor type roflumilast derivative, preparation method, composition and application 武汉科技大学 2026-05-12 CN claimed
US-20260115312-A1 Conjugates for neuroretinal drug delivery MIRECA MEDICINES GMBH (DE) 2026-04-30 US claimed
US-20260116886-A1 DEUTERATED sGC STIMULATORS TISENTO THERAPEUTICS INC (US) 2026-04-30 US claimed
US-12606618-B2 Antagonist anti-NPR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2026-04-21 US claimed
EP-0342015-A2 Peptides, their use and pharmaceutical compositions containing them IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) 1989-11-15 EP claimed
EP-0341264-A1 ATRIOPEPTINS, GUANYLATE CYCLASE ACTIVATORS, AND PHOSPHODIESTERASE INHIBITORS AS TREATMENT FOR GLAUCOMA, HYDROCEPHALUS AND CEREBRAL EDEMA (CRANIAL FLUID VOLUME DYSFUNCTION) THE GENERAL HOSPITAL CORPORATION (US) 1989-11-15 EP claimed
EP-0335386-A1 KS-506 compounds and process for the production thereof KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-10-04 EP claimed
WO-1988005306-A1 ATRIOPEPTINS, GUANYLATE CYCLASE ACTIVATORS, AND PHOSPHODIESTERASE INHIBITORS AS TREATMENT FOR GLAUCOMA, HYDROCEPHALUS AND CEREBRAL EDEMA (CRANIAL FLUID VOLUME DYSFUNCTION) THE GENERAL HOSPITAL CORPORATION (US) 1988-07-28 WO claimed
EP-0234854-A2 Use of phosphodiesterase inhibitors and cyclic nucleotide analogues for the manufacture of a medicament for stimulating tear secretion EYE RESEARCH INSTITUTE OF RETINA FOUNDATION (US) 1987-09-02 EP claimed
US-4623666-A CARDIOTONIC AGENTS, INCREASING CYCLIC GUANOSINE MONOPHOSPHATE KENNEDY THOMAS P 1986-11-18 US claimed
US-4554251-A PSEUDOMYREMEX TRIPLARINUS THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1985-11-19 US claimed
EP-0141182-A2 Process and medium for culturing ant venom gland cells THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1985-05-15 EP claimed
US-4433061-A ADDING A SOURCE OF DIVALENT CATION TO MINIMIZE INTERFERENCE OF CALCIUM CATIONS AMERICAN HOSPITAL SUPPLY CORPORATION (US) 1984-02-21 US claimed
US-4115538-A RADIOIMMUNOASSAY; ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE, GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE YAMASU SHOYU KABUSHIKI KAISHA (JP) 1978-09-19 US claimed