SCHEMBL18737202

SCHEMBL18737202

Nc1nc2c(ncn2C2OC3COP(=O)(O)OC4C(COP(=O)(O)OC3C2O)OC(n2cnc3c(=O)[nH]c(N)nc32)C4O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 18/20 1.00
PDE3B Q13370 1/20 1.00
PDE3A Q14432 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12671632 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL17974376 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL12634565 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL17325408 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL12634582 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL24467522 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL738 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL21470181 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL21498373 1.00 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL14980248 1.00 STING1 (1.00) STING1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025551-A1 COMPOSITIONS AND METHODS FOR INDUCING AND ENHANCING AN IMMUNE RESPONSE UNIV MICHIGAN STATE (US) 2025-01-23 US claimed
WO-2024201004-A1 COMBINATORIAL IL-15 THERAPY Prostate Cancer Research (GB) 2024-10-03 WO claimed
US-20220211842-A1 Methods and Devices for the Treatment of Food Allergies TEXAS TECH UNIVERSITY SYSTEM 2022-07-07 US claimed
CN-114080232-B Extracellular vesicles for vaccine delivery Lhasa Sales Co.,Ltd. (CH) 2026-05-26 CN disclosed
US-12629414-B2 Methods and devices for the treatment of food allergies TEXAS TECH UNIVERSITY SYSTEM (US) 2026-05-19 US disclosed
US-12616712-B2 Sting agonist comprising exosomes for treating neuroimmunological disorders LONZA SALES AG (CH) 2026-05-05 US disclosed
EP-4725557-A2 METHODS AND DEVICES FOR THE TREATMENT OF FOOD ALLERGIES Texas Tech University System (US) 2026-04-15 EP disclosed
EP-3630175-B1 METHODS AND DEVICES FOR THE TREATMENT OF FOOD ALLERGIES UNIV TEXAS TECH SYSTEM (US) 2026-03-11 EP disclosed
EP-4705451-A1 PROCESS FOR PREPARING EXTRACELLULAR VESICLES Lonza Sales AG (CH) 2026-03-11 EP disclosed
EP-4695405-A2 SMALL-MOLECULE REGULATED ALTERNATIVE SPLICING Rgenta Therapeutics, Inc. (US) 2026-02-18 EP disclosed
US-20260041764-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY LONZA SALES AG (CH) 2026-02-12 US disclosed
WO-2022066928-A2 PROCESS FOR PREPARING EXTRACELLULAR VESICLES CODIAK BIOSCIENCES, INC. (US) 2022-03-31 WO disclosed
CN-114080232-A Extracellular vesicles for vaccine delivery 科迪亚克生物科学公司 2022-02-22 CN disclosed
WO-2022036159-A2 IMMUNOSTIMULATORY BACTERIA-BASED VACCINES, THERAPEUTICS, AND RNA DELIVERY PLATFORMS Actym Therapeutics, Inc. (US) 2022-02-17 WO disclosed
US-11242521-B2 Obtainment of a rough-type Salmonella enteritidis and its genetic modifications for use as an avian vaccine FARMACOLOGICOS VETERINARIOS S.A.C.—FARVET 2022-02-08 US disclosed
EP-3941607-A1 PROCESS FOR PREPARING EXTRACELLULAR VESICLES Codiak BioSciences, Inc. (US) 2022-01-26 EP disclosed
EP-3941937-A2 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY Codiak BioSciences, Inc. (US) 2022-01-26 EP disclosed
US-10787479-B2 Crystalline 3′,5′-cyclic diguanylic acid YAMASA CORPORATION (JP) 2020-09-29 US disclosed
US-20190315795-A1 CRYSTALLINE 3',5'-CYCLIC DIGUANYLIC ACID YAMASA CORPORATION (JP) 2019-10-17 US disclosed
US-20170101432-A1 CRYSTALLINE 3',5'-CYCLIC DIGUANYLIC ACID YAMASA CORPORATION (JP) 2017-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041764-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY EXOSC10, EXOSC5, HLA-DRB1 STING1 109/4885PDE3B 2634/4885PDE3A 2978/4885
US-10787479-B2 Crystalline 3′,5′-cyclic diguanylic acid NT5C3B, GDA, GANC STING1 1787/4885PDE3B 260/4885PDE3A 103/4885
US-12616712-B2 Sting agonist comprising exosomes for treating neuroimmunological disorders STING1, TMIGD3, PLA2G4B STING1 1/4885PDE3B 1404/4885PDE3A 1232/4885
US-20170101432-A1 CRYSTALLINE 3',5'-CYCLIC DIGUANYLIC ACID GDA, NT5C3B, CA3 STING1 1708/4885PDE3B 241/4885PDE3A 90/4885
US-20190315795-A1 CRYSTALLINE 3',5'-CYCLIC DIGUANYLIC ACID GDA, NT5C3B, CA3 STING1 1708/4885PDE3B 241/4885PDE3A 90/4885
US-12629414-B2 Methods and devices for the treatment of food allergies CUTA, CD69, TSLP STING1 2560/4885PDE3B 4645/4885PDE3A 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.