Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 8/20 | 0.45 |
| ▸ | CTSS | P25774 | 8/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6580534 | 0.99 | CTSK (0.51) | CTSKSMN1; SMN2MAPK1CTSLCTSS | |
| Hydrochloric Acid SCHEMBL6580714 | 0.85 | CTSK (0.67) | CTSKCTSLCTSSCTSB | |
| Hydrochloric Acid SCHEMBL6582274 | 0.83 | CTSK (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7382726 | 0.83 | CTSK (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8810902 | 0.83 | CAPN1 (0.58) | CTSKCTSLCTSS | |
| SCHEMBL8810890 | 0.83 | CAPN1 (0.58) | CTSKCTSLCTSS | |
| Hydrochloric Acid SCHEMBL6580145 | 0.82 | CTSK (0.54) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580742 | 0.80 | CTSK (0.84) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580087 | 0.79 | CTSK (0.57) | CTSKSMN1; SMN2MAPK1CTSLCTSS | |
| SCHEMBL6582431 | 0.78 | CTSK (0.53) | CTSKSMN1; SMN2MAPK1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-A4 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 1999-10-13 | — | — | EP | disclosed |
| EP-0936912-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998005336-A1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | disclosed |