Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284064 | 1.00 | MEN1 (0.41) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| SCHEMBL29039196 | 1.00 | MEN1 (0.41) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| SCHEMBL31757881 | 1.00 | MEN1 (0.41) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| SCHEMBL7284071 | 1.00 | MEN1 (0.41) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| SCHEMBL10775306 | 1.00 | MEN1 (0.41) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL9872196 | 0.98 | MEN1 (0.39) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL7383292 | 0.98 | MEN1 (0.39) | MEN1BLMKMT2ASLC6A3SLC6A2 | |
| SCHEMBL19815556 | 0.94 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL19815510 | 0.94 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL4967575 | 0.81 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102282159-B | Peptide derivant and using binding substances form as the application of molecular vehicle | VECT-HORUS (FR) | 2015-11-25 | — | — | CN | disclosed |
| CN-102282159-A | Peptide derivatives and use thereof as carriers for molecules in the form of conjugates | — | 2011-12-14 | — | — | CN | disclosed |
| EP-0709373-B1 | PYRROLIDINE DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5965556-A | KETO-ACID AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHODS FOR INHIBITING THE ACTIVITY OF SERINE PROTEASE OR THIOL PROTEASE BY ADMINISTERING THE DERIVATIVE TO A MAMMAL; ALZHEIMER'S DISEASE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) | 1999-10-12 | — | — | US | disclosed |
| US-5756763-A | ENZYME INHIBITOR | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0468339-B1 | Alpha-keto-amide derivatives having protease inhibiting activity | NIPPON KAYAKU KK (JP) | 1997-04-09 | — | — | EP | disclosed |
| EP-0709373-A1 | NOVEL PYRROLIDINE DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |
| US-5221752-A | Inhibits prolyl endopeptidase activity; active ingredient of an enzyme inhibitor | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0468339-A2 | Alpha-keto-amide derivatives having protease inhibiting activity | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-01-29 | — | — | EP | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4200628-A | ANTIBIOTICS, BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1980-04-29 | — | — | US | disclosed |
| EP-0001643-A2 | Aminoglycoside derivatives, process for their manufacture, pharmaceutical compositions and carboxylic acids | SHIONOGI & CO., LTD. (JP) | 1979-05-02 | — | — | EP | disclosed |