Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.49 |
| ▸ | F10 | P00742 | 6/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27516341 | 0.98 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7389069 | 0.92 | ITGB3 (0.50) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7386932 | 0.91 | GRM2 (0.48) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7384096 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7390377 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7384783 | 0.88 | PRSS1 (0.46) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7421719 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8312934 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8317067 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7428581 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1281451-A | Benzamidine derivatives | MERCK PATENT GMBH (DE) | 2001-01-24 | — | — | CN | disclosed |
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |