Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681427 | 1.00 | LMNA (0.58) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL1681430 | 1.00 | LMNA (0.58) | LMNACYP2C19HSD17B10ACE | |
| Hydrochloric Acid SCHEMBL6325860 | 0.98 | LMNA (0.57) | LMNACYP2C19HSD17B10ACE | |
| Hydrochloric Acid SCHEMBL6325863 | 0.98 | LMNA (0.57) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL3709707 | 0.94 | LMNA (0.53) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL3709711 | 0.94 | LMNA (0.53) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL23013222 | 0.88 | LMNA (0.45) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL5702065 | 0.88 | LMNA (0.45) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL5702261 | 0.88 | LMNA (0.45) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL2036130 | 0.83 | LMNA (0.41) | LMNACYP2C19HSD17B10ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | claimed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | claimed |
| US-5135944-A | Bis(benzylpyrrolidine) derivatives useful for treating congestive heart failure and acute renal failure | SYNTEX (U.S.A.) INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5100912-A | Hypotensive agents, treatment of congestive heart failure | SYNTEX (U.S.A.) INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0426075-A1 | Benzylpyrrolidine derivatives as dopamine agonists | SYNTEX (U.S.A.) INC. (US) | 1991-05-08 | — | — | EP | disclosed |
| EP-0404115-A1 | Bis(benzylpyrrolidine)Derivatives as dopamine agonists | SYNTEX (U.S.A.) INC. (US) | 1990-12-27 | — | — | EP | disclosed |