Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.48 |
| ▸ | SDCBP | O00560 | 6/20 | 0.43 |
| ▸ | SDC2 | P34741 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382826 | 0.95 | REN (0.48) | RENSDCBPSDC2MAPTMEN1 | |
| SCHEMBL7382756 | 0.88 | REN (0.61) | RENSDCBPSDC2MAPTMEN1 | |
| SCHEMBL7384593 | 0.88 | REN (0.61) | RENSDCBPSDC2MAPTMEN1 | |
| SCHEMBL7383047 | 0.87 | REN (0.63) | RENSDCBPSDC2MAPTMEN1 | |
| SCHEMBL7382898 | 0.86 | REN (0.39) | RENMEN1KMT2A | |
| SCHEMBL7382869 | 0.84 | REN (0.60) | RENSDCBPSDC2MAPTMEN1 | |
| SCHEMBL7332395 | 0.79 | REN (0.77) | RENSDCBPSDC2MAPTMEN1 | |
| SCHEMBL7386226 | 0.76 | REN (0.60) | REN | |
| SCHEMBL7331420 | 0.74 | REN (0.61) | REN | |
| SCHEMBL7384315 | 0.74 | REN (0.52) | RENMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023338-A | Renin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-11 | — | — | US | claimed |